"The RhD protein which is the RHD gene product and a major component in the Rh blood group system carries the strongest blood group immunogen, the D antigen (Carritt et al. 1997, Flegel 2006). This antigen is absent in a significant minority (about 16%) of the Caucasian population (Rh-negatives) due to RHD deletion or alternation."
"Our present results indicate that RhD phenotype modulates the responses of the body not only to Toxoplasma infection, but also to other factors. Here we observed different correlations between two Cattell’s factors, namely dominance and shrewdness, and age in Rh-positive and Rh-negative subjects. In contrast to the response of the body to Toxoplasma infection, the correlation with the personality factors was stronger in Rh-positive subjects..."
Obviously, the difference between Rh-positive homozygotes and heterozygotes, namely permanent protection against the impairment of reaction times in heterozygotes and only temporary protection in homozygytes (Novotná et al. 2008), suggests that not (only) the RhD molecule but (also) a product of another gene in a strong genetic linkage with the RHD gene might be responsible for the observed biological and
psychological effects of RhD phenotype (Flegel 2006). To test such hypotheses, genetic instead of common serological data needs to be collected from larger populations."
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